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KMID : 0376219740110010313
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Chonnam Medical Journal
1974 Volume.11 No. 1 p.313 ~ p.329
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The Prenatal Development of the Lateral Nasal Wall in Human Fetuses
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Abstract
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With the histological method, the prenatal development of the lateral nasal wall and nasal conchae were studied on 45 cases of Korean fetuses varing in crown-rump lengths of 15mm to 320mm. Followings were the results of observations.
1. At 15mm fetus, the nasal cavity communicated freely with the oral cavity and the lateral wall showed two horizontal grooves along the wall outline the contour of the future inferior concha. The primordium of the lateral nasal wall could be recognized to appear as mesenchymal tissue from 15mm embryo and to complete the chondrification at 41mm fetus. At the 24mm fetus the formation of the palate by fusion of the palatal shelves became complete and earliest appearance of the inferior concha was observed.
2. Chondrification begun in the inferior concha at the 30mm fetus, and in the middle and superior conchae at the 41mm fetus. Endochondral bone formation was first noted by 60mm fetus in the inferior and middle conchae, and by 180mm -200mm fetuses in the superior concha. The maxillary and ethmoidal parts of the lateral nasal wall and three conchae were completely ossified in the 270mm fetus.
3. The membranous ossification center of maxilla and palatine were first seen at 17mm and 24mm respectively. In the 24mm fetus, a single ossification center of the maxilla appeared as a lamina which extended from the molar to incisor region. The primordium of the maxillary sinus was observed at 50mm fetus.
4. The earliest formation of gland of the respiratory mucosa appeared in the maxillary sinus in the 50mm fetus, whereas the glands were first evident in the inferior concha at 100mm fetus.
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KEYWORD
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